Translational misreading: a tRNA modification counteracts a +2 ribosomal frrm°P−X––qhift
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Translational misreading: a tRNA modification counteracts a +2 ribosomal frameshift.
Errors during gene expression from DNA to proteins via transcription and translation may be deleterious for the functional maintenance of cells. In this paper, extensive genetic studies of the misreading of a GA repeat introduced into the lacZ gene of Escherichia coli indicate that in this bacteria, errors occur predominantly by a +2 translational frameshift, which is controlled by a tRNA modif...
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تاریخ انتشار 2001